Evaluation of the Additional Effect of Vitix® Gel on Vitiligo Lesions in Patients Treated with Narrow-Band Ultraviolet-B Phototherapy

Vitiligo is a polygenic acquired skin disorder resulting from the destruction of melanocytes in epidermal cells. Conventional therapeutic options include covering agents, topical corticosteroids, immunomodulators, phototherapy with psolaren ultraviolet A (PUVA) and narrowband B (NBUVB). However, successful repigmentation these modalities expected only half patients. This study aimed to compare efficiency Vitix® gel combined NB-UVB versus alone treatment vitiligo lesions. Thirty patients were enrolled this study. All had relatively symmetrical lesions received combination on one side other side. Data analyzed using Wilcoxon Mann-Whitney tests. Twenty-five completed course (68% female, age: 32.3 ± 13.5 years). Five excluded due noncompliance follow-up. The highest response rate was observed upper limb’s no statistical difference treated after adjusting for age, sex lesions’ site (p > 0.05). Significant additional clinical not by adding NBUVB therapy